Microbial-host interactions involved in obesity and the response to bariatric surgery
Obesity has reached alarming levels in the UK. According to a government report, one in four adults are obese in the UK. Medical and dietary interventions are often ineffective at inducing weight loss and the best outcomes are obtained after weight loss surgery (also known as bariatric surgery). These surgical procedures were initially thought to work mechanistically through stomach restriction and lower calorie absorption through the shortened intestine. However, recent evidence has challenged this concept and it has been suggested that changes in the gut microbial flora could affect metabolism contributing to weight loss and increased insulin response. Gut flora is beneficial to the host in many ways, contributing to for example, nutrient absorption and a healthy immune system. Abnormalities in the composition of the gut microbes are thought to contribute to the pathology of certain diseases, including obesity and diabetes.
Date: 15 November 2018, 14:00 (Thursday, 6th week, Michaelmas 2018)
Venue: MRC Weatherall Institute of Molecular Medicine, Headington OX3 9DS
Venue Details: Seminar Room
Speakers: Dr Alessandra Geremia (University of Oxford ), Dr Carolina Arancibia (University of Oxford), Dr Valentina Greto (University of Oxford)
Organising department: NDM Experimental Medicine
Organiser: Dr Carolina Arancibia (University of Oxford)
Organiser contact email address: carolina.arancibia@ndm.ox.ac.uk
Part of: BRC3 Gastroenterology and Mucosal Immunity Theme Seminars
Booking required?: Not required
Audience: Members of the University only
Editor: Jayne Jefferies