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Computational investigation of single-scale and multi-scale heterogeneous immune responses during cancer evolution
Tumour microenvironment is characterised by heterogeneity at various scales: from various cell populations (immune cells, cancerous cells, …) and various molecules that populate the microenvironment (cytokines, chemokines, extracellular vesicles, …); to phenotype heterogeneity inside the same cell population (e.g., immune cells with different phenotypes and different functions); as well as temporal heterogeneity in cells’ phenotypes (as cancer evolves through time) and spatial heterogeneity.
In this talk we overview some mathematical models and computational approaches developed to investigate different single-scale and multi-scale aspects related to heterogeneous immune responses during cancer evolution. Throughout the talk we emphasise the qualitative vs. quantitative results, and data availability across different scales
Date:
14 February 2025, 11:00
Venue:
Mathematical Institute, Woodstock Road OX2 6GG
Venue Details:
L4
Speaker:
Prof Raluca EFTIMIE (Université de Franche-Comté, Besançon)
Organising department:
Mathematical Institute
Organiser:
Sara Jolliffe (University of Oxford)
Organiser contact email address:
jolliffe@maths.ox.ac.uk
Host:
Prof Jose Carrillo (University of Oxford)
Part of:
Mathematical Biology and Ecology
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Sara Jolliffe
