A brain-wide analysis of entorhinal projections
Complementary actions of the neocortex and the hippocampus enable encoding and long-term storage of experience dependent memories. Standard models for memory storage assume that sensory signals reach the hippocampus from superficial layers of the entorhinal cortex (EC). Deep layers of the EC on the other hand relay hippocampal outputs to the telencephalic structures including many parts of the neocortex. In this seminar I will present new insights into how entorhinal outputs to the brain are wired to disseminate hippocampal outputs to outside of the hippocampal area, introduce a new feedback route for hippocampal outputs and discuss the implications of these findings for learning and memory.
Date: 4 March 2022, 13:00 (Friday, 7th week, Hilary 2022)
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: The Blakemore Lecture Theatre
Speaker: Gülşen Sürmeli (Royal Society and Wellcome Trust, Sir Henry Dale Fellow, Centre for Discovery Brain Sciences, University of Edinburgh)
Organising department: Department of Physiology, Anatomy and Genetics (DPAG)
Organisers: Dr Adam Packer (University of Oxford), Associate Professor Duncan Sparrow (DPAG, University of Oxford)
Organiser contact email address: hod-pa@dpag.ox.ac.uk
Host: Dr Adam Packer (University of Oxford)
Part of: DPAG Head of Department Seminar Series
Booking required?: Not required
Audience: Members of the University only
Editor: Talitha Smith