The multilayered identity of B cell memory


In-person only

​​​A hallmark of the adaptive immune system is its ability to generate long-lasting memory that protects ​against reinfections. In antibody-mediated responses, memory is maintained by plasma cells and memory B-cells (MBCs), with a diverse pool of MBCs being important for responses to new pathogen ​variants. Mechanisms underlying MBCs’ longevity, rapid responsiveness, and diversity remain ​largely unknown. This talk will focus on published and unpublished results that unravel key aspects of MBC heterogeneity and how this influences their function and maintenance.​​