Sleep and Circadian Neuroscience Institute Seminar Series: Coordinating brain and peripheral tissue clocks: the role of the circadian system in regulating cardiac function
Please ensure you take your seats before 5pm so we can start promptly.
Most organisms use internal biological (circadian) clocks to match behavioural and physiological processes to specific phases of the external world. Central to this is the synchronisation of internal processes across the brain and multiple organ systems. We are now keenly aware that disruption of our circadian system is detrimental to health and wellbeing. For example, environmental desynchrony (e.g. shift work) profoundly impacts human health, increasing cardiovascular disease and diabetes risk, many diseases show diurnal variation in severity of symptoms, and risk of clinically adverse events can vary across the day and night. In this seminar, I will discuss our work on the role played by the circadian system in driving daily rhythms in electrical activity in the heart, time of day vulnerability to arrhythmia and the impact of mistimed behavioural rhythms on cardiac function.
Date: 18 May 2023, 17:00 (Thursday, 4th week, Trinity 2023)
Venue: Sherrington Building, off Parks Road OX1 3PT
Venue Details: Blakemore Lecture Theatre
Speaker: Dr David Bechtold (University of Manchester)
Organising department: Nuffield Department of Clinical Neurosciences
Organiser: Toria Summers (University of Oxford)
Organiser contact email address: toria.summers@ndcn.ox.ac.uk
Booking required?: Not required
Audience: Members of the University only
Editor: Jacqueline Pumphrey