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Host-pathogen interactions in the diseased lung
Individuals with chronic lung diseases such as cystic fibrosis and COPD are particularly vulnerable to bacterial infections. Clinically, these infections are challenging to manage and often persist for years, leading to chronic, difficult-to-treat infections. Over time, the bacteria diversify and adapt to the lung environment and the antibiotics used in treatment. In this talk, I will present our work using metagenomics and spatial transcriptomics to unravel bacterial adaptation and host-pathogen interactions. Our findings are transforming our fundamental understanding of chronic lung infections.
Date:
10 November 2025, 13:30
Venue:
Life and Mind Building, South Parks Road, OX1 3EL, seminar rooms 7 & 8, Lower Ground Floor
Speaker:
Dr Josie Bryant (Wellcome Sanger Institute)
Organising department:
Department of Biology
Organiser:
Andrea Kastner (Department of Biology)
Organiser contact email address:
andrea.kastner@biology.ox.ac.uk
Host:
Dr Craig Maclean (Department of Biology University of Oxford)
Booking required?:
Not required
Audience:
Members of the University only
Editor:
Andrea Kastner