The evolutionary trajectory of vertebrate adaptive immune systems
This is a hybrid event - with the speaker attending in-person and viewable on Teams.
Lymphocytes of vertebrate adaptive immune systems acquired the capability to assemble, from split genes in the germline, billions of functional antigen receptors. I will, discuss the co-evolutionary origin of somatic diversification of antigen receptors and programmable genome editors, the evolutionary trajectory of quality control mechanisms that suppress undesired self-reactivity, and the unusual structures of immunogenomes of species exercising natural parabiosis
Date: 7 March 2024, 12:00 (Thursday, 8th week, Hilary 2024)
Venue: MRC Weatherall Institute of Molecular Medicine, Headington OX3 9DS
Venue Details: Seminar Room
Speaker: Dr Thomas Boehm (The Max Planck Institute of Immunobiology & Epigenetics, Munich)
Organising department: MRC Weatherall Institute of Molecular Medicine
Organiser: Yasmine Saito (Weatherall Institute, University of Oxford)
Organiser contact email address: seminar.admin@imm.ox.ac.uk
Host: Oliver Bannard
Booking required?: Recommended
Booking email: seminar.admin@imm.ox.ac.uk
Audience: Members of the University only
Editor: Yasmine Saito