Imaging heart formation and function in zebrafish
Didier Stainier’s group investigates questions related to organogenesis including cell differentiation, tissue morphogenesis, organ homeostasis and function, as well as organ regeneration. In particular, they study these questions in zebrafish and utilize both forward and reverse genetic approaches, and aim to dissect cellular processes using high-resolution live imaging. Zebrafish, Danio rerio, offers unique advantages as a vertebrate genetic system and is also ideal for embryological studies. The zebrafish heart is accessible for continued observation and manipulation at all stages of development and offers single cell resolution of its components. Through several genome-wide screens in zebrafish, they have identified a large number of mutations that affect heart formation and function.
Date: 27 November 2015, 11:00 (Friday, 7th week, Michaelmas 2015)
Venue: NDM Building, Headington OX3 7FZ
Venue Details: TDI, Basement Seminar Room
Speaker: Prof Didier Stainier (Max Planck Institute for Heart and Lung Research)
Organising department: Ludwig Institute for Cancer Research, Oxford Branch
Organisers: Mary Muers (Oxford Ludwig Institute, NDM Experimental Medicine), Alexandra Ward (University of Oxford, Oxford Ludwig Institute, NDM Experimental Medicine)
Host: Prof Xin Lu (Ludwig Cancer Research, Oxford Branch)
Part of: Ludwig Institute Seminar Series
Booking required?: Not required
Audience: Members of the University only
Editor: Mary Muers