OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Dr Pimanda will present results from a body of work using functional genomics to develop tools to predict drug response in Myelodysplasia (MDS), identify alternate treatment options for patients who fail current treatment and characterise treatment related changes to the sub-clonal architecture and function of dysplastic haematopoietic stem/progenitor cells (HSPCs). He will also present an integrative analysis of long intergenic non-coding RNA (lincRNAs) expression from 922 acute myeloid leukemia patients. These analyses show that leukemic and normal hematopoietic cell subsets express distinct lincRNAs and that gene signatures composed of as few as three lincRNA genes are independent predictors of clinical outcome across multiple patient cohorts.