Molecular Pathology is the interrogation of clinical samples to a) understand better the nature of diseases; or b) to diagnose, prognosticate or decide on therapeutic intervention of diseases. As such, it is a relevant component of basic and translational research operations.
This lecture will provide examples on how Molecular Pathology has helped in the generation of laboratory information to support hypothesis on molecular mechanisms of disease, or to understand the clinical relevance of basic science discoveries. In the process, we will discuss the technical approaches to these applications and how molecular pathology can be integrated in research institutes to facilitate discovery and translation.