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My laboratory works on understanding the basis for immunity to infections and autoimmunity. Specifically, we are trying to define mechanisms of signal transduction by cytokines and their receptors. Our main focus is the interleukin-17 superfamily of receptors. Our research is aimed at defining the molecular and biochemical structure-function relationships in the IL-17R complex, as well as the role of Th17 cells at the oral mucosa.
