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To report or not to report? That's not the only question!
Next generation sequencing technologies (NGS) such as whole genome, whole exome, and large panels of genes, are rapidly changing the paradigm of medicine. Widespread use of NGS carries with it many ethical and practical challenges, some of which persist despite considerable debate. Whether laboratories and clinics should report variants of uncertain significance (VUS) to clinicians and/or patients, reinterpret VUS in response to the growing knowledge in the field, reissue reports to clinicians based on any revised classifications, and recontact patients, are all key unsolved issues in the clinical use of NGS. In addition, the question of whether, and to what extent, unsolicited findings (also known as incidental findings) should be returned to patients following NGS remains unanswered. In this presentation, Danya will discuss these issues, drawing on data from a systematic analysis 58 consent forms being used in the diagnostic setting to investigate their policies.
Date:
13 June 2018, 11:00
Venue:
Big Data Institute (NDM), Old Road Campus OX3 7LF
Venue Details:
Seminar room 0
Speaker:
Danya Vears (Center for Biomedical Ethics and Law Department of Public Health and Primary Care, KU Leuven)
Organisers:
Christa Henrichs (Wellcome Centre for Ethics and Humanities),
Jane Beinart (University of Oxford)
Hosts:
The Ethox Centre,
Wellcome Centre for Ethics and Humanities (University of Oxford)
Part of:
Wellcome Centre for Ethics and Humanities and Ethox Centre
Booking required?:
Required
Booking email:
weh@bdi.ox.ac.uk
Audience:
Public
Editor:
Christa Henrichs
