G-actin as a signalling molecule

Richard Treisman studies the ways in which signalling pathways can lead to specific gene activation, including in the context of cancer and development. His research uses a broad range of biochemical, genomic and cell biological approaches. In particular, he has worked extensively on the transcriptional regulator SRF and the Myocardin Related Transcription Factor (MRTF) family, which are G-actin binding proteins.