OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
A consistent feature of lung injury is a rapid and sustained accumulation of the extracellular matrix component hyaluronan (HA). Increased HA is found in the lungs after infection with SARS-CoV2 or influenza but also during asthma and allergy or exposure to pollutants. Here, I’ll present our recent work showing that the type-2 cytokine IL-13 is required for HA matrix formation in several models of lung challenge. Our aim now is to understand how IL-13 regulates these matrices and understand how HA accumulation and formation of specific HA matrices either contributes to effective tissue repair or drives lung pathology.