Initiating and persisting mechanisms of Parkinson’s neurodegeneration from environmental risk factors

Dr. Briana De Miranda is a Neurotoxicologist and Assistant Professor of Neurology within the Killion Center for Neurodegeneration and Experimental Therapeutics at University of Alabama at Birmingham (UAB). Her research examines the role of environmental exposures in the risk for Parkinson’s disease and Lewy body disorders, with a central focus on mechanisms of neurotoxicity that drive dopaminergic neurodegeneration and alpha-synuclein aggregation. Her lab at UAB specializes in experimental systems of exposure that recapitulate environmental conditions found in human populations, including inhalation of organic solvents and contaminated drinking water.