OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Déborah Bourc’his’ team is focused on understanding the nature and the role of the epigenetic information in gametogenesis, fertilization and early embryonic development. Her work is mostly centered on DNA methylation, how it influences gametic production and integrity, and impacts on phenotypes at following generations. Studying the epigenetic setting of germ cells allows investigation of several crucial aspects of mammalian biology such as transposon control, genomic imprinting and early lineage commitment. Studying DNA methylation in the window of conception leads also to mechanistic insights into the spatio-temporal control of genomic methylation specificity, including components of histone modification and RNA-directed pathways. Her work uses fine developmental and molecular dissection, combined with genetic tools (CRISPR) and genome-wide sequencing approaches.
