OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Within tissues, dendritic cells constitute a complex cell population composed of distinct subsets that can exhibit different activation states and functions. How tissue-specific cues orchestrate dendritic cell diversification remains elusive. In the first part of my seminar, I will discuss unpublished results showing that, by reaching distinct sub-tissular niches within the gut, dendritic cells can exist as immature and mature cells, revealing a novel mechanism of dendritic cell functional diversification. In the second part of my seminar, I will present data highlighting the essential role of macrophages in protecting colonic epithelial cells from being poisoned by fungi toxins. I will discuss the implications of these findings on colon inflammation and cancer.