External Seminar: Intricate regulation of T cell effector function through post-transcriptional events

If you would like to attend this seminar, please contact adminsupport@oncology.ox.ac.uk for the MS Teams link.

Dr. Wolkers did her PhD in Ton Schumacher’s lab. After her postdoctoral training with Stephen Schoenberger (La Jolla Institute), Douglas Green (St. Jude’s Memphis), and Jan-Paul Medema (AmsterdamUMC-AMC), Dr. Wolkers started her group in 2010 at Sanquin Research, Amsterdam. Since then, she is fascinated by the molecular mechanisms that dictate CD8 T-cell effector function. Her group showed for instance that post-transcriptional mechanisms define the production of pro-inflammatory cytokines and define their capacity to kill tumors and infected cells. Furthermore, her group uncovered surface markers that can distinguish cytotoxic from non-cytotoxic T cells, a tool that may be important for the development of effective T-cell therapies. Monika holds an ERC consolidator grant and is an Oncode Investigator.