A journey from fibrositis to central sensitization to nociplastic pain

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Nociplastic pain is now the term preferred by pain scientists to explain a syndrome wherein pain occurs in the absence of ongoing nociceptive input or nerve damage. The term most pain researchers used prior to this for this phenomena was central sensitization. However rheumatologists referred to the individuals who most obviously clinically displayed these symptoms, and originally this entity was termed fibrositis – until it became clear there was no -itis in this condition and it was renamed fibromyalgia. Research into fibromyalgia and a number of chronic overlapping pain conditions has helped formed the basis for our mechanistic understanding of nociplastic pain as well as what treatments are effective for these conditions.