OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Chronic hepatitis B virus (HBV) infection presents a significant global health challenge, characterized by substantial morbidity and mortality rates worldwide. Despite the existence of a preventive vaccine, current treatment options offer limited efficacy in clearing the virus, necessitating lifelong management. The diagnosis and prognosis of HBV heavily rely on its surface antigen (HBsAg). However, despite extensive research efforts, detailed high-resolution structures of HBsAg and its assembly on the virus envelope have remained elusive.
We have employed sophisticated strategies and advanced computational tools to uncover the near-atomic resolution structure of HBsAg and its assembly.