Oxford Events, the new replacement for OxTalks, will launch on 16th March. From now until the launch of Oxford Events, new events cannot be published or edited on OxTalks while all existing records are migrated to the new platform. The existing OxTalks site will remain available to view during this period.
From 16th, Oxford Events will launch on a new website: events.ox.ac.uk, and event submissions will resume. You will need a Halo login to submit events. Full details are available on the Staff Gateway.
Centrosomes are small cytoplasmic organelles that generate and organize microtubule networks, and thus contribute to a multitude of cellular processes including cell division, polarity and trafficking. For instance, centrosomes drive mitotic spindle assembly whilst cytolytic immune cells depend on centrosomal microtubule arrays for the targeted release of secretory lysosomes. Emerging evidence suggests that centrosomes also act as signalling hubs; due to their membraneless nature, these organelles are able to concentrate (and possibly scaffold) components of signalling pathways from the cytosol. Furthermore, in many cell types, centrosomes template assembly of the primary cilium, an antenna-like cell surface organelle with prominent roles in Hedgehog, Wnt and Notch signalling. To fulfil these complex roles, cells must accurately control centrosome number, composition, structure and function. My group combines cell biology, super-resolution and live microscopy, mouse genetics and proteomics to determine physiological roles and regulation of centrosomes, and to probe the impact of centrosome aberrancies on human pathologies.
