The Diatchenko lab investigates the psychological, molecular, cellular, and genetic pathways that mediate both acute and persistent pain. A primary goal of her laboratory is to identify the critical elements of human genetic variability contributing to pain sensitivity and pathological pain states. In this talk Professor Diatchenko will discuss how genome-wide genetic and transcriptomic data analysis lead to understanding of molecular pathophysiology of pain states and enable individualized treatments and therapies. The analysis of both human clinical samples and animal pain models will be discussed.