OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
The cell plasma membrane and its underlying actin cytoskeleton constitute an active composite system that acts as a platform for multiple tasks such as signal processing, cargo uptake or shape transitions to name a few. Using reconstituted, minimal systems, we expllore how acto-myosin activity drives membrane protein dynamics and vice versa how membrane proteins can affect the actin network organization. Studying LAT-based biomolecular condensates that form during T cell activation, we found that Nck and WASP act as a molecular clutch with actin and that changes in the condensate composition could enable their movement by different actin networks.
