OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Finding novel treatments that protect motor neurons from degeneration remains a cornerstone of therapeutic development for motor neuron diseases such as ALS and SMA. In this talk I will present my lab’s identification of bioenergetics pathways as important, endogenous regulators of motor neuron stability in vivo. I will discuss how activation of PGK1 represents an attractive therapeutic in this regard, and present ongoing work to translate pre-clinical findings into clinical trials for patients with ALS.
