Immune alterations in first-episode psychosis and the effects of natalizumab: A neuroimaging study with concurrent CSF measures

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Immune alterations in first-episode psychosis and the effects of natalizumab: A neuroimaging study with concurrent CSF measures

It is hypothesised that microglia, the primary immune cells in the brain, play a key role in the pathophysiology of schizophrenia. To address this, we investigated the effects of 3-month treatment with the monoclonal antibody natalizumab on a PET biomarker of microglia, CSF cytokines, and symptom measures in people with first-episode psychosis. I will be presenting unpublished findings from this study and future directions.

This seminar is hosted in person at the Department of Psychiatry, Common Room. To join online, please use the Zoom details below:

zoom.us/j/97330056859?pwd=rrLAlrOoptEYpaDkWovAKhGqUjpYV4.1

Meeting ID: 973 3005 6859
Passcode: 649983

Date: 15 October 2025, 11:00
Venue:
Department of Psychiatry
Headington OX3 7JX
See location on maps.ox

Details: Gelder room
Speaker: Dr Yuya Mizuno (King's College London)
Organising department: Department of Psychiatry
Organiser: Professor Andrea Cipriani (University of Oxford)
Organiser contact email address: rania.elgarf@psych.ox.ac.uk
Host: Professor Robert McCutcheon (University of Oxford)
Part of: Psychiatry Seminar Series
Booking required?: Not required
Audience: Public
This talk features in the following public collections:
- Talks of Interest to Medical Sciences
Editor: Rania Elgarf