Oxford Events, the new replacement for OxTalks, will launch on 16th March. The two-week OxTalks freeze period starts on Monday 2nd March. During this time, there will be no facility to publish or edit events. The existing OxTalks site will remain available to view during this period. Once Oxford Events launches, you will need a Halo login to submit events. Full details are available on the Staff Gateway.
Stromal cells are fibroblasts that provide the supportive framework of an organ and its vasculature, distinct from the parenchyma. Extending from the vasculature, these cells are also strategically positioned to sense local inflammation and support tissue immunity. The immunological functions of stromal cells are best exemplified in lymphoid organs, where they steer the recruitment, retention and activation of adaptive immune responses. Many of these immunological functions are recapitulated in inflamed, non-lymphoid organs with consequences for local immunity and tissue pathology. We have previously contributed to elucidating mechanisms by which lymphoid organ fibroblasts support efficient humoral immunity. Our current work focuses on elucidating how stromal cell immunobiology is shaped by interacting immune cell partners and tissue environments, with a particular focus on the central nervous system and its draining lymphoid organs.