OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Spines are ubiquitous morpho-functional elements of excitatory synaptic transmission and plasticity in the neocortex. Whether functional spines are also present in the thalamus is currently unclear. Here I demonstrate that layer 5 cortico-thalamic terminals arising from several frontal cortical regions preferentially target functional spines in the thalamus via variable and complex synapses. These axo-spinous L5-thalamic connections are surprisingly powerful, able to selectively recruit a subset of thalamic neuron and are involved in motor learning.