OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
For our next talk, in the Digital Phenotyping seminar series, we will hear from Dr Yi-Cong Zhi, postdoctoral researcher in machine learning for infectious diseases, Big Data Institute, on Wednesday 14 January, 2:00 pm – 3:00 pm, at the Big Data Institute (BDI).
Title: Bayesian machine learning enables discovery of risk factors for hepatosplenic multimorbidity related to schistosomiasis
Date: Wednesday 14 January
Time: 2:00 pm – 3:00 pm
Venue: BDI/OxPop, Seminar Room 0; followed by refreshments in the atrium
Abstract:
One in 25 deaths worldwide is related to liver disease, and often with multiple hepatosplenic conditions. Yet, little is understood of the risk factors for hepatosplenic multimorbidity, especially in the context of chronic infections. We present a novel Bayesian multitask learning framework to jointly model 45 hepatosplenic conditions assessed using point-of-care B-mode ultrasound for 3155 individuals aged 5-91 years within the SchistoTrack cohort across rural Uganda where chronic intestinal schistosomiasis is endemic. We identified distinct and shared biomedical, socioeconomic, and spatial risk factors for individual conditions and hepatosplenic multimorbidity, and introduced methods for measuring condition dependencies as risk factors. Notably, for gastro-oesophageal varices, we discovered key risk factors of older age, lower hemoglobin concentration, and schistosomal periportal fibrosis. Our findings provide a compendium of risk factors to inform surveillance, triage, and follow-up, while our model enables improved prediction of hepatosplenic multimorbidity, and if validated on other anatomical systems, general multimorbidity.
Hybrid Option:
Please note that these meetings are closed meetings and only open to members of the University of Oxford. Please respect our speakers and do not share the link with anyone outside of the University. The purpose of these seminars is to foster more communication among employees throughout the University, so we strongly advise in-person attendance whenever feasible.
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