OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Germinal centers (GCs) are microanatomical sites of B cell clonal expansion and antibody affinity maturation. Driving the GC reaction are a specialized subset of T cells called T follicular helper (Tfh) cells. Tfh engage in cognate ineractions with GC B Cells, leading to GC expansion. However, it has become evident in later times that the GC harbors multiple subsets of T cells, and that they serve a role in controlling the rise and fall of the GC. We are investigating the role of different T cells in GC kinetics, and how this ultimately effects the quality of GC B cells.