OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Adaptive immune responses unfold within complex tissue microenvironments that shape clonal selection, effector fate, and long-term immune resilience. I will discuss new spatial transcriptomic technologies we’ve developed which capture the state, receptor sequence, and location of lymphocytes directly in situ. These approaches reveal how T and B cell diversity is organized across germinal centers, inflamed tissues, and aging thymus. By integrating clonal and spatial information, we can map how immune interactions and tissue cues drive adaptation, regeneration, and decline, offering a framework for decoding adaptive immunity across health, aging, and disease.
