On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
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Towards New Antibiotics – Targeting Penicillin Binding Proteins
The lecture will begin by giving some thoughts on possible reasons as to why β-lactams remain the most important antibacterials after more than 70 years of use. Mechanisms of resistance to the β-lactams will be described, focussing on the β-lactamases. A review of attempts to develop non β-lactams targeting the penicillin binding protein (PBP) targets of β-lactams and β-lactamases will be given. Work aimed at the development of single compounds targeting PBPs and both metallo and serine β-lactamases will be described.
