On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
If you have any questions, please contact halo@digital.ox.ac.uk
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer marked by severe immune suppression and abnormal inflammation that promote tumor growth. Recent research identified IL-1b+ tumor-associated macrophages (TAMs) as a subset that drives inflammatory changes and influences nearby tumor cells. Using spatial gene expression analysis we explored the physical distribution and local interactions of IL-1b+ TAMs and within human PDAC tissue. The findings revealed distinct clustering of immune and non-immune cells into specific multicellular hubs, suggesting potential immune-mediated pathways that could be targeted for therapeutic strategies.