On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
If you have any questions, please contact halo@digital.ox.ac.uk
Cryo-EM single particle analysis is undergoing rapid changes. In this
talk, I will discuss how developments in sensitive and fast direct
electron detectors yield movies with relatively high signal-to-noise
ratios, and how new image processing techniques to deal with
beam-induced motions and structurally heterogeneous samples are now
yielding near-atomic resolution reconstructions for a wide range of
specimens. I will illustrate the potentials of these methods by
highlighting our recent results on various structures of human
gamma-secretase, the intramembrane protease complex responsible for
cleavage of amyloid precursor protein.
