Oxford Events, the new replacement for OxTalks, will launch on 16th March. From now until the launch of Oxford Events, new events cannot be published or edited on OxTalks while all existing records are migrated to the new platform. The existing OxTalks site will remain available to view during this period.
From 16th, Oxford Events will launch on a new website: events.ox.ac.uk, and event submissions will resume. You will need a Halo login to submit events. Full details are available on the Staff Gateway.
A pipeline was developed to quantify EBV DNA from whole-genome sequencing data in a cohort of over half million subjects identifying 39 susceptibility risk loci. A significant overlap with genetic variants associated with MS risk was observed p<10-12. These data suggest that EBV-infected B cells may constituted a critical hub that modulates T cell responses while activating MS gene linked susceptibility pathways within B cells. Finally, B cell depletion is almost totally effective in stopping autoimmune MS. Thus, we define a genetic and cellular framework linking B cells to the initiation of MS and support a causal role of EBV activity on MS risk.
