On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
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I will discuss our work on the phagocyte NADPH oxdase (NOX2). This crucial multi-subunit complex generates reactive oxygen species (ROS) to kill pathogens but is also essential for immune regulation. We have described EROS as a crucial chaperone for NOX2 assembly and inflammasome signalling. I will present some published work and unpublished findings on EROS’s role in adaptive immunity and a novel regulator of reactive oxygen species generation. I will then describe how investigating the Duox2-Duoxa2 system in ROS generation led us to discover an essential role of thyroid hormone in NK cell biology. This is a collaboration with Alice Denton (Imperial College).
