OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
I will describe research in two areas of interest to my laboratoy: (1) electron cryotomography and three-dimensional reconstruction of the thin edge of frozen-hydrated cells to understand cytoskeletal architecture and to understanding the packaging of von Willebrand factor (VWF) in rod-shape granules in endothelial cells called Weibel-Palade bodies (WPBs). (2) three-dimensional reconstruction of lipid-enveloped influenza viruses to understand virus assembly and entry into cells during infection. Lastly, I will discuss methods for improving cryomicroscopy images from the molecular to the cellular scale.