MitOX is our annual meeting packed with short talks and posters on cancer metabolism, neuroscience, diabetes, mitochondrial disorders and general mitochondrial biology. This one day hybrid conference is ideal for researchers with an interest in mitochondria from both academia and pharma.
For more info, please see webpage: www.wrh.ox.ac.uk/news/mitox-2025
9.25 Karl Morten (Oxford) Welcome
Session 1. Mitochondrial Biology
9.30 Luis Tabara Rodriguez (University of Cambridge): Mitochondrial fusion selectivity controls mitochondrial recycling to maintain mtDNA levels
9.55 Gautam Wali (University of Melbourne): Single-Cell Image Analysis Uncovers Mitochondrial and Lysosomal Defects in Parkinson’s Diseas
10.20 Robbie Baldock (University of Portsmouth) Investigating the mechanisms of mitochondrial DNA mutagenesis and repair: ST1
10.35 Jan Willem Taanman (UCL): Inhibition of mitochondrial protein synthesis induces biosynthesis of oxidative phosphorylation Complex V and reverses its activity: ST2
10.50 Coffee
Session 2. Novel Approaches to Investigate mitochondrial Dysfunction
11.20 Ryan Carter (University of Oxford): Integrative Radiogenomics with 18F-Fluciclovine PET Highlights Reprogramming of Pyrimidine Metabolism in Primary Breast Cancer
11.45 Ladislav Valkovic (University of Oxford): Using Magnetic Resonance Spectroscopy to non-invasively detect mitochondrial dysfunction in Long Covid and ME/CFS
12.10 Sheeza Mughal (IBEC, Barcelona). Developing artificial 3-D skeletal muscle tissues to investigate altered metabolic and functional dynamics in ME/CFS and Long COVID-19.
12.35 James Sleigh (UCL): In vivo imaging of axonal mitochondrion transport and morphology in genetic peripheral neuropathy.
13.00 Lunch & Poster session
Session 3. Mitochondrial Therapies
14.15 Pollard Lecture Jan Renwinkel (University of Oxford): Induction of innate immunity by mitochondrial RNA.
14.40 Millie Fullerton (University of Newcastle): Mitochondrial dysfunction in a model of dilated cardiomyopathy is rescued by vitamin supplementation
15.05 Mara Artibani (University of Oxford): Targeting the metabolic vulnerabilities of chemotherapy-resistant ovarian cancer
15.30 Ana Victoria Lechuga-Vieco (IRB Barcelona): Metabolic Remodeling Through Mitochondrial Transfer: A Key to Enhanced Immune Responses: ST3
15.45 Tea
Session 4. Mitochondria in Physiology and Disease
16.15 Enrique Rodriguez (UCL): Anaesthetics disrupt complex I-linked respiration and reverse the ATP synthase: insights into the mechanism of consciousness
16.40 Brent Ryan (University of Oxford): Novel methods to understand the role of mitochondrial dysfunction in neurodegeneration.
17.05 Hanmin Lee (City St George’s, University of London): Characterising MRPL44 Transgenic Mouse Model: Insights into Mitochondrial Disorder Pathogenesis and Sex-Dependent Responses.ST4
17.20 Micol Falabella (UCL): Biallelic PTPMT1 variants disrupt cardiolipin metabolism and lead to a neurodevelopmental syndrome. ST5
17.35 Poster Prizes and wrap up
17.45 Drinks