Dr. Kapoor is involved in the health relevance of virome dynamics and development of surrogate models for human viruses. His work has led to the identification of non-primate homologs of Hepatitis C virus, including the well-known equine and rodent hepaciviruses. Recently he has been characterizing the biological properties of these new HCV-like animal viruses using in vitro and reverse genetic systems, paving the way for their detailed in vivo characterization.