OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
In recent years there has been an explosion in both the amount of next-generation sequencing performed on cancers and in the number of computational methods used to analyse the generated data. Focusing on cancer evolution and heterogeneity, I describe the findings of my research through both large-scale projects such as the International Cancer Genome Consortium and smaller-scale studies of individual tumour types, including prostate, oesophageal, colorectal, breast and haematological cancers. These findings cover a range of topics, including: progression from benign neoplasms to cancer; mechanisms of metastatic spread; changes in mutational processes during cancer progression; variable subclonal response to treatment; the importance of the order of acquisition of driver mutations.
