On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
If you have any questions, please contact halo@digital.ox.ac.uk
In recent years there has been an explosion in both the amount of next-generation sequencing performed on cancers and in the number of computational methods used to analyse the generated data. Focusing on cancer evolution and heterogeneity, I describe the findings of my research through both large-scale projects such as the International Cancer Genome Consortium and smaller-scale studies of individual tumour types, including prostate, oesophageal, colorectal, breast and haematological cancers. These findings cover a range of topics, including: progression from benign neoplasms to cancer; mechanisms of metastatic spread; changes in mutational processes during cancer progression; variable subclonal response to treatment; the importance of the order of acquisition of driver mutations.