OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Abstract: The pancreatic ATP-sensitive K+ channel (Katp) is a key regulator of insulin secretion due to its ability to couple the membrane potential to changes in intracellular glucose metabolism and is the receptor for the widely-used anti-diabetic sulfonylurea drugs. Greg, a PhD student with Prof. Show-Ling Shyng in Portland Oregon, has been using recent advances in cryo-EM to reveal near-atomic details of channel gating and regulation by sulfonylureas, while also confirming many of the in-depth functional experiments conducted over the last three decades.
