Seminar by Prof Shane Crotty "Adaptive Immunity and Immune Memory to SARS-CoV-2 after COVID-19"

This seminar will be held virtually via Zoom at 3pm and is open to Oxford university members only, registration is at:

Understanding immune memory to SARS-CoV-2 is critical for improving diagnostics and vaccines, and for assessing the likely future course of the COVID-19 pandemic. We analyzed multiple compartments of circulating immune memory to SARS-CoV-2 from 188 COVID-19 cases, including 43 samples at > 6 months post-infection. By studying antibody, memory B cell, CD4+ T cell, and CD8+ T cell memory to SARS-CoV-2 in an integrated manner, we observed that each component of SARS-CoV-2 immune memory exhibited distinct kinetics (Dan et al., Science 2021). I will also present a working model of the relationship between adaptive immune responses and COVID-19 disease.