HDRUK Oxford Monthly Meetup, Monday 20 October 2025, 2:00 pm – 3:00 pm

Speaker: Dr Charlie Harper, Trial Data Scientist, NDPH

Mode: Hybrid
In person venue: Richard Doll Building Lecture Theatre
To attend online – please register (link below)

Short Bio:
Charlie is a Trial Data Scientist working in the Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU) at Oxford Population Health and the Data Linkage Lead for the ASCEND-PLUS trial. His work aims to develop new trial methods to streamline large-scale randomised trials that produce reliable answers, including the use of healthcare systems data to recruit and follow-up participants.

Abstract:
Large-scale randomised trials are increasingly costly and resource intensive to conduct, thus limiting the size and duration of follow-up of contemporary clinical trials. Streamlining trials by re-using healthcare systems data offers the opportunity to conduct more efficient trials at scale. In this talk Charlie will (1) present the theory behind utilising such data in clinical trials, (2) outline recent findings about how reliable healthcare systems data are in ascertaining trial outcomes; and (3) illustrate its use in the ASCEND-PLUS randomised trial of semaglutide versus placebo in people with diabetes.