OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
The dorsal striatum receives a major and topographic input from the cortex, and the cortex and striatum are thought to work together to carry out a diverse set of functions. It is unclear how the cortex and striatum influence each other however, and it has been suggested that each carries distinct sensorimotor correlates to serve complementary roles. We sought to record from connected regions of the cortex and striatum in mice during sensory guided behavior to determine the relationship of activity across structures. We found precise spatial correlations in activity following anatomical projections from the cortex to the striatum, and activity in the striatum reflected that in associated cortical regions consistently across behavioral contexts. This match in activity was scaled by learning, as untrained mice exhibited smaller sensory responses selectively in the striatum. These results suggest a simple and scalable mapping of activity between the cortex and striatum.