OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Immune responses unfold within tissues whose architecture and composition fundamentally shape inflammation and its resolution. Understanding these processes requires integrating spatial tissue structure with cellular dynamics and function. In this seminar, we will explore advanced imaging and computational approaches that connect single-cell behavior with tissue-level organization. By combining multiplex 3D microscopy, quantitative analysis, and in vivo functional imaging, we examine how tissue macrophages interact with stromal networks to sustain homeostasis or promote dysfunction. Through this framework, we will discuss how spatial tissue organization may set local inflammation thresholds and govern the shift from physiological repair to pathological disease.