Oxford Events, the new replacement for OxTalks, will launch on 16th March. The two-week OxTalks freeze period starts on Monday 2nd March. During this time, there will be no facility to publish or edit events. The existing OxTalks site will remain available to view during this period. Once Oxford Events launches, you will need a Halo login to submit events. Full details are available on the Staff Gateway.
Pharmacological MRI studies rely on the assumption that haemodynamic measures can be considered a proxy of altered neurotransmission. However, the fMRI signal has no intrinsic selectivity to any particular receptor sites and the degree to which haemodynamic response indexes the action at drug target sites is still an open question. To address this issue, we developed REACT (Receptor-Enriched Analysis of functional Connectivity by Targets), a multimodal method that enriches the resting state fMRI analysis with the molecular information about the distribution density of specific receptors in the brain. With this new approach, we are able to show that drug-induced functional effects can be understood through the distribution of their main targets.
