The ins and outs of cellular quiescence

Alexis started her scientific training during her Undergraduate and Masters degrees in Natural Sciences at the University of Cambridge. She remained in Cambridge for her PhD research into centrosomes and mitotic spindle assembly which she did with Fanni Gergely at the CRUK Cambridge Institute. In 2010 she moved to London for her Postdoctoral work with Chris Bakal at the Institute of Cancer Research. There, she started to investigate cell cycle entry and to develop tools to be able to use single-cell imaging and mathematical modelling to understand this heterogeneous phenomenon. In 2018, Alexis was awarded a CRUK Career Development Fellowship and she started her own research group at the MRC-Laboratory of Medical Sciences (LMS) at Imperial College London in September 2018. In April 2024, she was awarded the British Society of Cell Biology Women in Cell Biology Award. Her team is trying to decipher how cells transition between proliferating and non-proliferating states and how this information can be manipulated to improve cancer treatment.