Oxford Events, the new replacement for OxTalks, will launch on 16th March. From now until the launch of Oxford Events, new events cannot be published or edited on OxTalks while all existing records are migrated to the new platform. The existing OxTalks site will remain available to view during this period.
From 16th, Oxford Events will launch on a new website: events.ox.ac.uk, and event submissions will resume. You will need a Halo login to submit events. Full details are available on the Staff Gateway.
Our work is focused on malformations of the face and cranium, particularly the premature fusion of the joints (“sutures”) between the bones of the skull vault (this is called craniosynostosis). A web of developmental mechanisms is involved in organising this complex system of bones, and a variety of genetic mutations can affect these processes to cause serious skull malformations. The talk will move from the identification of new genetic causes of craniosynostosis, through modelling in mice and induced pluripotent stem cell (iPSC) lines to establish causality and investigate pathogenic mechanisms, to a discussion of what the human and mouse genetics tell us about normal cranial suture and skull development.
