OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Stromal-derived Follicular Dendritic Cells (FDCs) are indispensable for the orchestration of germinal centers (GCs), the epicenter of B cell antibody maturation. Despite their pivotal role, the transcriptome of human FDCs remains an enigma. Leveraging single-cell RNA sequencing and microarray analyses, we present a comprehensive transcriptomic portrait of these elusive cells, validated through flow cytometry and microscopy. This has led to surprising insights and new study directions, which I will discuss. Perhaps there is more regulation in de GC than we thought.