OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
I studied for my PhD at Imperial College London, where I was working on the regulation of cell-cell adhesion by small GTPases. My work explored how nutrient starvation impacted the spatio-temporal activity of these proteins, an area which I have continued to focus on throughout my career. My postdoctoral work at Newcastle University and now, as a Wellcome-funded Research Fellow in the School of Biochemistry at University of Bristol, is focused on understanding the molecular cell biology of the nutrient-responsive mTORC1-autophagy axis. The pro-growth mTORC1 pathway and the degradative autophagy-lysosome pathway control the dynamic balance between biosynthesis, degradation and recycling to maintain cellular proteostasis and homeostasis. We are studying the mechanisms controlling the spatial regulation and activity of these processes and how rewiring of this equilibrium contributes to cellular senescence (a tumour suppressor mechanism of cell cycle arrest).
