OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
The autonomic nervous system is central to homeostatic regulation of the heart across physiological states. In the setting of chronic cardiac injury, initially protective adaptive mechanisms orchestrated by the autonomic nervous system become deleterious. Structural and functional remodelling of neuronal and non-neuronal elements comprising reflex heart-brain circuits promote maladaptive processes that worsen cardiac function and enhance arrhythmias. Employing approaches ranging from in silico to mechanistic clinical studies, our work elucidates mechanisms governing adverse neural remodelling and develops interventions targeting nexus points within heart-brain reflex circuits to treat chronic heart disease.
